Concepedia

CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance

Suryaprakash Raichur, Siew Tein Wang, Puck Wee Chan, Ying Li, Jianhong Ching, Bhagirath Chaurasia, Shaillay Kumar Dogra, Miina K. Öhman, Kosuke Takeda, Shigeki Sugii,

Cell Metabolism · 2014 · 453 citations · 20 references

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20

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Timothy R. Koves, John R. Ussher, Robert C. Noland et al. · Cell Metabolism · 2008 · 2K citations · Full text

, , +16

Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

Sarah M. Turpin-Nolan, Hayley T. Nicholls, Diana M. Willmes et al. · Cell Metabolism · 2014 · 686 citations · Full text

, , +12

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

William L. Holland, Benjamin T. Bikman, Liping Wang et al. · Journal of Clinical Investigation · 2011 · 681 citations · Full text

, , +17

A Ceramide-Centric View of Insulin Resistance

Jose A. Chavez, Scott A. Summers · Cell Metabolism · 2012 · 595 citations · Full text

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Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas

Silke Imgrund, Dieter Hartmann, Hany Farwanah et al. · Journal of Biological Chemistry · 2009 · 305 citations · Full text

, , +17