Concepedia

CD69 downregulates autoimmune reactivity through active transforming growth factor-β production in collagen-induced arthritis

David Sancho, Manuel Gómez‐Florit, Fernando Viedma, Enric Esplugues, Mónica Gordón‐Alonso, María Ángeles García-López, Hortensia de la Fuente, Carlos Martínez‐A, Pilar Lauzurica, Francisco Sánchez‐Madrid

Journal of Clinical Investigation · 2003 · 159 citations · 48 references

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Abstract

tions In addition, NK cell-dependent tumor rejection is favored in the absence of CD69 (13). However, the functional role of CD69 expressed by T cells and macrophages at inflammatory sites and in autoimmune processes has not been explored.

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