Angewandte Chemie · 2012 · 13 citations · 27 references
Life SciencesBiochemistryMetabolismMicrobial MetabolismNatural Product BiosynthesisMetabolic Pathway ChemistryNucleotide MetabolismPrebiotic ChemistryFormamide ChemistryNucleotide Synthesis PathwaysPurine BiosynthesisPurine ChemistryUnified Process
Ausgehend von Formamid werden Mechanismen für die Umwandlung in Purin und Adenin vorgeschlagen (siehe Schema: Purin (R=H, X=H), Adenin (R=CN, X=NH2, R′=CONH2). Parallelen zu diesen plausiblen präbiotischen Routen könnten zu den Ursprüngen der metabolischen Purinring-Biosynthese führen. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Synthesis of adenine from ammonium cyanide
J. Oró · Biochemical and Biophysical Research Communications · 1960 · 472 citations