Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists

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Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

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Analytical molecular surface calculation

Michael L. Connolly · Journal of Applied Crystallography · 1983 · 2.5K citations

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[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

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The neurobiology of vascular head pain

Michael A. Moskowitz · Annals of Neurology · 1984 · 912 citations

Life Sciences, Neurobiology, Neuroscience +17

Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

J.E. Leysen, F. Awouters, Ludo Kennis et al. · Life Sciences · 1981 · 846 citations

Medicine, Medicinal Chemistry, Pharmacology +13