Catalytic Asymmetric Synthesis of Complex Polypropionates: Lewis Base Catalyzed Aldol Equivalents in the Synthesis of Erythronolide B

Abstract

8 aus 10: Stereoselektive, Lewis-Base-katalysierte aldolanaloge Reaktionen lieferten acht der zehn Stereozentren, die für die Synthese von Erythronolid B benötigt werden. Insgesamt wurden sogar alle elf Stereozentren des Erythromycin-Aglycons direkt oder indirekt über katalytische asymmetrische aldolanaloge Additionen erhalten (siehe Schema). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.