Optimization of DOTAP/chol Cationic Lipid Nanoparticles for mRNA, pDNA, and Oligonucleotide Delivery

Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.

Jiin Felgner, Rajesh Kumar, Ch. Sridhar et al. · Journal of Biological Chemistry · 1994 · 1.3K citations · Full text

Pharmacy, Biochemistry, Pharmaceutics +17

Viral and nonviral delivery systems for gene delivery

Nayerossadat Nouri, Maedeh Talebi, PalizbanAbas Ali · Advanced Biomedical Research · 2012 · 852 citations · Full text

Pharmacy, Biotechnology, Genetics +17

Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer

Olga B. Garbuzenko, Yechezkel Barenholz, Aba Priev · Chemistry and Physics of Lipids · 2005 · 314 citations

Natural Sciences, Biochemistry, Materials Engineering +14

Cholesterol modulates the liposome membrane fluidity and permeability for a hydrophilic molecule

Samar Kaddah, Nathalie Khreich, Fouad Kaddah et al. · Food and Chemical Toxicology · 2018 · 287 citations

Natural Sciences, Biochemistry, Biophysics +14

Nonbilayer phase of lipoplex–membrane mixture determines endosomal escape of genetic cargo and transfection efficiency

Inge S. Zuhorn, Udo Bakowsky, Evgeny Polushkin et al. · Molecular Therapy · 2005 · 264 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +10