Tracy A. Brooks

Demonstration that Drug-targeted Down-regulation of MYC in Non-Hodgkins Lymphoma Is Directly Mediated through the Promoter G-quadruplex

Robert V. Brown, Forest Danford, Vijay Gokhale et al. · Journal of Biological Chemistry · 2011 · 167 citations · Full text

Non-hodgkins Lymphoma, Immunology, Drug-targeted Down-regulation +17

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

Tracy A. Brooks, Brian T. Hawkins, Jason D. Huber et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2005 · 149 citations · Full text

Chronic Inflammatory Pain, Pain Medicine, Immunology +25

Epigenetic Modification, Dehydration, and Molecular Crowding Effects on the Thermodynamics of i-Motif Structure Formation from C-Rich DNA

Yogini P. Bhavsar-Jog, Eric Van Dornshuld, Tracy A. Brooks et al. · Biochemistry · 2014 · 123 citations · Full text

Molecular Crowding Effects, Molecular Biology, Epigenetics +19

Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.

Tracy A. Brooks, Hans Minderman, Kieran L. O’Loughlin et al. · PubMed · 2003 · 118 citations

Tumor Biology, Health Sciences, Medicine +14

Anticancer Activity and Cellular Repression of c-MYC by the G-Quadruplex-Stabilizing 11-Piperazinylquindoline Is Not Dependent on Direct Targeting of the G-Quadruplex in the c-MYC Promoter

Peda V. L. Boddupally, Seongmin Hahn, Cristina Beman et al. · Journal of Medicinal Chemistry · 2012 · 113 citations · Full text