Genetic associations of adult height with risk of cardioembolic and other subtypes of ischemic stroke: A mendelian randomization study in multiple ancestries

Andrew Brent Linden, Robert Clarke, Imen Hammami, Jemma C. Hopewell, Yu Guo, William Whiteley, Kuang Lin, Iain Turnbull, Yiping Chen, Canqing Yu,

PLoS Medicine · 2022 · 23 citations · 24 references

DOIFull text

Open access

Abstract

The findings provide support for a causal association of taller adult height with higher risk of cardioembolic stroke and lower risk of other ischemic stroke subtypes in diverse ancestries. Further research is needed to understand the shared biological and physical pathways underlying the associations between height and stroke risks, which could identify potential targets for treatments to prevent stroke.

References

24