The UK Biobank resource with deep phenotyping and genomic data

Clare Bycroft, Colin Freeman, Desislava Petkova, +16

Nature

Accurate proteome-wide missense variant effect prediction with AlphaMissense

Jun Cheng, Guido Novati, Joshua Pan, +13

Science

GeneticsGenetic EpidemiologyGenomicsGenome-wide Association StudyBiostatistics +14

Genome-wide genetic data on ~500,000 UK Biobank participants

Clare Bycroft, Colin Freeman, Desislava Petkova, +13

GeneticsGenetic EpidemiologyUnited KingdomGenomicsGenetic Medicine +22

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates

Anjali Gupta Hinch, Philipp Becker, Tao Li, +8

Molecular Cell

ChromatinGenome InstabilityCell DivisionDmc1 BindingGenetics +10

Patterns of genetic differentiation and the footprints of historical migrations in the Iberian Peninsula

Clare Bycroft, Ceres Fernández–Rozadilla, Clara Ruíz-Ponte, +4

Nature Communications

AlphaGenome: advancing regulatory variant effect prediction with a unified DNA sequence model

Žiga Avsec, Natasha S. Latysheva, Jun Cheng, +23

EngineeringNeurogenomicsGeneticsGene CharacterizationGenomics +20

Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe

Alessandro Raveane, Serena Aneli, Francesco Montinaro, +44

Science Advances

Patterns of genetic differentiation and the footprints of historical migrations in the Iberian Peninsula

Clare Bycroft, Ceres Fernández–Rozadilla, Clara Ruíz-Ponte, +4

Human MigrationGeneticsSpanish IndividualsGenetic DiversityMolecular Ecology +19

Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe

Alessandro Raveane, Serena Aneli, Francesco Montinaro, +42

Advancing regulatory variant effect prediction with AlphaGenome

Žiga Avsec, Natasha S. Latysheva, Jun Cheng, +24

Nature