Concepedia

Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial

Joseph P. Casazza, Evan M. Cale, Sandeep Narpala, Galina V. Yamshchikov, Emily E. Coates, Cynthia S. Hendel, Laura Novik, LaSonji A. Holman, Alicia T. Widge, Preeti Apte,

Nature Medicine · 2022 · 94 citations · 50 references

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Concepts

References

50

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

Supachai Rerks‐Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan et al. · New England Journal of Medicine · 2009 · 3K citations · Full text

, , +12

Antibody neutralization and escape by HIV-1

Xiping Wei, Julie M. Decker, Shuyi Wang et al. · Nature · 2003 · 2.4K citations

, , +12

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

, , +9

Long-Term Safety and Efficacy of Factor IX Gene Therapy in Hemophilia B

Amit Nathwani, Ulreke M. Reiss, Edward G. D. Tuddenham et al. · New England Journal of Medicine · 2014 · 1.3K citations · Full text

, , +17

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

Jinghe Huang, Gilad Ofek, Leo Laub et al. · Nature · 2012 · 847 citations · Full text

, , +11