The grapefruit polyphenol naringenin inhibits multiple cardiac ion channels

Prevalence of the Congenital Long-QT Syndrome

Peter J. Schwartz, Marco Stramba‐Badiale, Lia Crotti et al. · Circulation · 2009 · 1.1K citations

Life Sciences, Cardiology, Genetics +14

Plasma Kinetics and Urinary Excretion of the Flavanones Naringenin and Hesperetin in Humans after Ingestion of Orange Juice and Grapefruit Juice

Iris Erlund, Esa Meririnne, Georg Alfthan et al. · Journal of Nutrition · 2001 · 501 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

MICE Models: Superior to the HERG Model in Predicting Torsade de Pointes

James Kramer, Carlos A. Obejero‐Paz, Glenn J. Myatt et al. · Scientific Reports · 2013 · 352 citations · Full text

Medicine, Cardiology, Pharmacology +17

The genetics underlying acquired long QT syndrome: impact for genetic screening

Hideki Itoh, Lia Crotti, Takeshi Aiba et al. · European Heart Journal · 2015 · 211 citations · Full text

Life Sciences, Cardiology, Genetics +12

Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram*

Robert Benton, Peter K. Honig, Kaveh Zamani et al. · Clinical Pharmacology & Therapeutics · 1996 · 182 citations

Medicine, Pharmacokinetics, Pharmacology +13