Concepedia

CD34+THY1+ synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro

Seiji Noda, Tadashi Hosoya, Yoji Komiya, Yasuhiro Tagawa, Kentaro Endo, Keiichiro Komori, Hideyuki Koga, Yasuhiro Takahara, Kazutaka Sugimoto, Ichiro Sekiya,

Arthritis Research & Therapy · 2022 · 18 citations · 40 references

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Abstract

The CD34<sup>+</sup>THY1<sup>+</sup> SF subset has high osteogenic and chondrogenic potentials. The preferential enhancement of MSC functions in the CD34<sup>+</sup>THY1<sup>+</sup> subset may provide a new treatment strategy for regenerating damaged bone/cartilage in arthritic joints.

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