In Vitro-In Vivo Correlation of Blood–Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans

Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors

Yasuo Uchida, Sumio Ohtsuki, Yuki Katsukura et al. · Journal of Neurochemistry · 2011 · 909 citations

Life Sciences, Biochemistry, Pharmacology +15

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

Shinsuke Nakagawa, Mária A. Deli, Hiroko Kawaguchi et al. · Neurochemistry International · 2008 · 735 citations · Full text

Medicine, Neurobiology, Neuroscience +12

Structure−Brain Exposure Relationships in Rat and Human Using a Novel Data Set of Unbound Drug Concentrations in Brain Interstitial and Cerebrospinal Fluids

Markus Fridén, Susanne Winiwarter, Gunilla Jerndal et al. · Journal of Medicinal Chemistry · 2009 · 225 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat.

Gwyn H. Evans, Alan S. Nies, David G. Shand · PubMed · 1973 · 206 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Passage of cefotaxime and ceftriaxone into cerebrospinal fluid of patients with uninflamed meninges

Roland Nau, Hilmar Prange, P. Muth et al. · Antimicrobial Agents and Chemotherapy · 1993 · 140 citations · Full text

Medicine, Infectious Diseases, Pharmacology +12