Concepedia

Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir

Sven Ullrich, Kasuni B. Ekanayake, Gottfried Otting, Christoph Nitsche

Bioorganic & Medicinal Chemistry Letters · 2022 · 198 citations · 29 references

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29

A Novel Coronavirus from Patients with Pneumonia in China, 2019

Na Zhu, Dingyu Zhang, Xingwang Li et al. · New England Journal of Medicine · 2020 · 30.4K citations · Full text

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On the size of the active site in proteases. I. Papain

Israël Schechter, Arieh Berger · Biochemical and Biophysical Research Communications · 1967 · 5.2K citations

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Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome

Christian Drosten, Stephan Günther, Wolfgang Preiser et al. · New England Journal of Medicine · 2003 · 4.8K citations · Full text

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Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

Zhenming Jin, Xiaoyu Du, Yechun Xu et al. · Nature · 2020 · 4.5K citations · Full text

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Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

Linlin Zhang, Daizong Lin, Xinyuanyuan Sun et al. · Science · 2020 · 3.4K citations · Full text

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