Concepedia

Effects of Tumor Mutational Burden and Gene Alterations Associated with Radiation Response on Outcomes of Postoperative Radiation Therapy in Non-Small Cell Lung Cancer

Narek Shaverdian, Annemarie F. Shepherd, Xingzhe Li, Michael Offin, Harry B. Lengel, Daphna Y. Gelblum, Abraham J. Wu, Charles B. Simone, Andreas Rimner, David R. Jones,

International Journal of Radiation Oncology*Biology*Physics · 2022 · 26 citations · 34 references

DOIFull text

Open access

Concepts

References

34

Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

Naiyer A. Rizvi, Matthew D. Hellmann, Alexandra Snyder et al. · Science · 2015 · 7.8K citations · Full text

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

Robert Samstein, Chung‐Han Lee, Alexander N. Shoushtari et al. · Nature Genetics · 2019 · 4.2K citations · Full text

, , +9

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

Ahmet Zehir, Ryma Benayed, Ronak Shah et al. · Nature Medicine · 2017 · 3.4K citations · Full text

, , +12

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

Nicholas McGranahan, Andrew J.S. Furness, Rachel Rosenthal et al. · Science · 2016 · 3K citations

, , +20

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)

Donavan T. Cheng, Talia Mitchell, Ahmet Zehir et al. · Journal of Molecular Diagnostics · 2015 · 2.1K citations

, , +13