Concepedia

Publication | Open Access

Synergistic Anti-Tumor Effect of Combining Selective CDK7 and BRD4 Inhibition in Neuroblastoma

DOIFull Paper Access

23

Citations

33

References

2022

Year

Yang Gao, Marina P. Volegova, Nicole Nasholm, Sanjukta Das, Nicholas Kwiatkowski, Brian J. Abraham, Tinghu Zhang, Nathanael S. Gray, Clay Gustafson, Małgorzata Krajewska,
Frontiers in Oncology

Abstract

The combination of CDK7 and BRD4 inhibition provides a therapeutic option for neuroblastoma and suggests that the addition of YKL-5-124 could improve the therapeutic efficacy of JQ1 and delay resistance to BRD4 inhibition.

References

YearCitations

Page 1