Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

Janel E. Le Belle, Nicolas M. Orozco, Andres A. Paucar et al. · Cell stem cell · 2011 · 792 citations · Full text

Neuroregeneration, Molecular Neuroscience, Developmental Biology +13

Increased Alzheimer's disease–like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy

Gururaj Joshi, Kok Ann Gan, Delinda A. Johnson et al. · Neurobiology of Aging · 2014 · 175 citations · Full text

Cell Autophagy, Neurodegenerative Diseases, Neurobiology Of Disease +12

Increased Expression but Reduced Activity of Antioxidant Enzymes in Alzheimer's Disease

Rawhi Omar, Yau‐Jan Chyan, Anne C. Andorn et al. · Journal of Alzheimer s Disease · 1999 · 148 citations

Lipid Peroxidation, Neurochemical Biomarkers, Antioxidant Enzymes +21

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

Tahir Ali, Gwang Ho Yoon, Shahid Ali Shah et al. · Scientific Reports · 2015 · 147 citations · Full text

Neuroprotective Effect of Caffeic Acid Phenethyl Ester in A Mouse Model of Alzheimer’s Disease Involves Nrf2/HO-1 Pathway

Fabiana Morroni, Giulia Sita, Agnese Graziosi et al. · Aging and Disease · 2018 · 134 citations · Full text