1,6-Addition of 1,2,3-NH triazoles to<i>para</i>-quinone methides: Facile access to highly selective N¹and N²substituted triazoles

Abstract

Regioselective syntheses of N 1 and N 2 substituted triazoles via 1,6-addition of 1,2,3-NH triazole with p -QM were developed under mild reaction conditions. Isomerization of N 1 to N 2 substituted triazoles was also achieved in the presence of AlCl 3 .