Substrate Scope Expansion
Substrate Scope Expansion is a methodological strategy in whole-cell biocatalysis that broadens the range of non-native substrates a microbial biocatalyst can transform by engineering cellular uptake, efflux, or intracellular metabolic pathways to enhance substrate accessibility and turnover.
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2017–2026
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Xiaohua Huang, Kevin W. Anderson, Danilo Zim et al. · Journal of the American Chemical Society · 2003 · 767 citations
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Shanghai Institute of Organic Chemistry
Shanghai, China
65 h-index
488 publications
32.1K citations

Chinese Academy of Sciences
Beijing, China
64 h-index
641 publications
38.9K citations

Nankai University
Tianjin, China
40 h-index
223 publications
12.1K citations
University of Chinese Academy of Sciences
Beijing, China
36 h-index
282 publications
14.2K citations
Lanzhou University
Lanzhou, China
35 h-index
275 publications
11.7K citations
University of Science and Technology of China
Hefei, China
34 h-index
181 publications
12.1K citations

Sichuan University
Chengdu, China
33 h-index
310 publications
15.5K citations

University of Göttingen
Göttingen, Germany
30 h-index
121 publications
13K citations
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JACS · 154 publications · 20.3K citations
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OL · 604 publications · 29.6K citations
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JOC · 310 publications · 11.7K citations
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ChemComm · 146 publications · 6.3K citations
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