Concepedia

MrgprX2 regulates mast cell degranulation through PI3K/AKT and PLCγ signaling in pseudo-allergic reactions

Fan Zhang, Fang Hong, Lu Wang, Renjie Fu, Jin Qi, Boyang Yu

International Immunopharmacology · 2021 · 32 citations · 20 references

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20

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

Benjamin D. McNeil, Priyanka Pundir, Sonya Meeker et al. · Nature · 2014 · 1.3K citations

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Polydatin inhibits mast cell-mediated allergic inflammation by targeting PI3K/Akt, MAPK, NF-κB and Nrf2/HO-1 pathways

Jing Ye, Hongmei Piao, Jingzhi Jiang et al. · Scientific Reports · 2017 · 133 citations · Full text

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G protein coupled receptor specificity for C3a and compound 48/80-induced degranulation in human mast cells: Roles of Mas-related genes MrgX1 and MrgX2

Sakeen W. Kashem, Hariharan Subramanian, Sarah J. Collington et al. · European Journal of Pharmacology · 2011 · 110 citations · Full text

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Use of the relative release index for histamine in LAD2 cells to evaluate the potential anaphylactoid effects of drugs

Shengli Han, Yanni Lv, Liyun Kong et al. · Scientific Reports · 2017 · 52 citations · Full text

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Differential Ca2+ mobilization and mast cell degranulation by FcεRI- and GPCR-mediated signaling

Ying‐Chi Chen, Yu-Chung Chang, Heng-Ai Chang et al. · Cell Calcium · 2017 · 48 citations

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