Concepedia

Publication | Open Access

An <i>In Vivo</i> CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression

DOIFull Paper Access

30

Citations

31

References

2021

Year

Manuel C. Scheidmann, Francesc Castro-Giner, Karin Strittmatter, Ilona Krol, Aino Paasinen-Sohns, Ramona Scherrer, Cinzia Donato, Sofia Gkountela, Barbara M. Szczerba, Zoi Diamantopoulou,
Cancer Research

Abstract

A loss-of-function CRISPR screen in human CTC-derived xenografts identifies genes critical for individual steps of the metastatic cascade, suggesting novel drivers and treatment opportunities for metastatic breast cancers.

References

YearCitations

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