Concepedia

Eculizumab in patients with severe coronavirus disease 2019 (COVID-19) requiring continuous positive airway pressure ventilator support: Retrospective cohort study

Piero Ruggenenti, Fabiano Di Marco, Monica Cortinovis, Ferdinando Luca Lorini, Sílvia Carbonell Sala, Luca Novelli, Federico Raimondi, Sara Gastoldi, Miriam Galbusera, Roberta Donadelli,

PLoS ONE · 2021 · 42 citations · 17 references

DOIFull text

Open access

Abstract

In patients with severe COVID-19, eculizumab safely improved respiratory dysfunction and decreased the combined endpoint of mortality and discharge with chronic complications. Findings need confirmation in randomised controlled trials.

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