Concepedia

Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity

Mahmoud A. Ragab, Mohamed Elagawany, Hoda G. Daabees, Al‐Shaimaa F. Ahmed, Eman M. Awad, Cyrielle Billon, Bahaa Elgendy, Khaled A. M. Abouzid, Shaymaa E. Kassab

Bioorganic Chemistry · 2021 · 12 citations · 66 references

DOI

Concepts

References

66

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

, , +10

Cloning of a novel receptor expressed in rat prostate and ovary.

George G. J. M. Kuiper, Eva Enmark, Markku Pelto‐Huikko et al. · Proceedings of the National Academy of Sciences · 1996 · 4.8K citations

, , +12

Molecular basis of agonism and antagonism in the oestrogen receptor

A.M. Brzozowski, A.C.W. Pike, Zbigniew Dauter et al. · Nature · 1997 · 3.3K citations

, , +14

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

Andrew K. Shiau, D. Barstad, Paula M. Loria et al. · Cell · 1998 · 2.7K citations · Full text

, , +14

Pyrazole Ligands:  Structure−Affinity/Activity Relationships and Estrogen Receptor-α-Selective Agonists

Shaun R. Stauffer, Christopher J. Coletta, Rosanna Tedesco et al. · Journal of Medicinal Chemistry · 2000 · 760 citations

, , +17