RNA circles with minimized immunogenicity as potent PKR inhibitors

Fast gapped-read alignment with Bowtie 2

Ben Langmead, Steven L. Salzberg · Nature Methods · 2012 · 58.3K citations · Full text

Long-read Sequencing, Sequence Assembly, Natural Sciences +7

ViennaRNA Package 2.0

Ronny Lorenz, Christian Höner zu Siederdissen, Hakim Tafer et al. · Algorithms for Molecular Biology · 2011 · 5.1K citations · Full text

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

Luigi Warren, Philip D. Manos, Tim Ahfeldt et al. · Cell stem cell · 2010 · 2.6K citations · Full text

Synthetic Modified Mrna, Induced Pluripotent Stem Cell, Engineering +14

5'-Triphosphate RNA Is the Ligand for RIG-I

Veit Hornung, Jana M. Ellegast, Sarah Kim-Hellmuth et al. · Science · 2006 · 2.4K citations

Viral Replication, Systems Biology, Engineering +12

Complementary Sequence-Mediated Exon Circularization

Xiao‐Ou Zhang, Haibin Wang, Yang Zhang et al. · Cell · 2014 · 2.1K citations · Full text

Sequence Design, Sequence Motif, Molecular Biology