MiR-499a-5p promotes 5-FU resistance and the cell proliferation and migration through activating PI3K/Akt signaling by targeting PTEN in pancreatic cancer - Concepedia

Concepedia

Publication | Open Access

MiR-499a-5p promotes 5-FU resistance and the cell proliferation and migration through activating PI3K/Akt signaling by targeting PTEN in pancreatic cancer

DOI Full Paper Access

24

Citations

25

References

2021

Year

Liu Ouyang, Rendong Liu, De-Qiao Lei, Qing-Chao Shang, Huifen Li, Xiangui Hu, Hao Zheng, Gang Jin

Annals of Translational Medicine

Abstract

Taken together, these findings demonstrate that miR-499a-5p can be potentially applied to PC therapy.

References

	Year	Citations
Analyzing real-time PCR data by the comparative CT method Thomas D. Schmittgen, Kenneth J. Livak Nature Protocols Computed TomographyImage AnalysisEngineeringMedical ImagingBiomedical Imaging	2008	26K
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 Jacques Ferlay, Hai‐Rim Shin, Freddie Bray, International Journal of Cancer Cancer ManagementEpidemiology Of CancerWorldwide IncidencePathologyCancer Registration	2010	21.3K
Cancer statistics, 2019 Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal CA A Cancer Journal for Clinicians Epidemiology Of CancerPopulation Health SciencesHealth DisparitiesCancer RegistrationMortality Rates	2019	20.7K
MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer Fanyin Meng, Roger Henson, Hania Wehbe–Janek, Gastroenterology Microrna-21 Regulates ExpressionMedicinePathologyHuman Hepatocellular CancerSmall Rna	2007	2.8K
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia Takuya Matsunaga, Naofumi Takemoto, Tsutomu Sato, Nature Medicine Hematological MalignancyMixed-phenotype Acute LeukemiaHematologyImmunologyPathology	2003	542
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo Jason T. Huse, Cameron Brennan, Dolores Hambardzumyan, Genes & Development Pten LocusCancer BiologyGliomaTumor BiologyPten-regulating Microrna Mir-26a	2009	508
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities Mariella G. Filbin, Sukriti K. Dabral, Maria F. Pazyra‐Murphy, Nature Medicine Neuro-oncologyPten-deficient GlioblastomaSignal TransductionSignaling PathwayGlioma	2013	150
microRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4 Xiangqiang Liu, Zhiyong Zhang, Li Sun, Carcinogenesis OncologyCrc Cell MigrationMedicineColorectal CancerPathology	2011	146
MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer Y Zhang, Geoffrey A. Talmon, Jinling Wang Cell Death and Disease	2015	107
Exosomal miR-499a-5p promotes cell proliferation, migration and EMT via mTOR signaling pathway in lung adenocarcinoma Shan He, Ziming Li, Yongfeng Yu, Experimental Cell Research Extracellular VesiclesMedicineLung AdenocarcinomaExosomal Mir-499a-5p PromotesExtracellular Microvesicles	2019	105

Page 1