An experimental comparison of classification algorithms for hierarchical prediction of protein function

Andrew Secker, Matthew N Davies, Alex A. Freitas, Jon Timmis, Miguel Mendao, Darren R. Flower

Kent Academic Repository (University of Kent) · 2007 · 41 citations · 10 references

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Abstract

Some data can be naturally organised as a hierarchy of classes. The classification of data in such a hierarchy poses some unique challenges to data miners. One particular case of this is the classification of GPCR proteins by their function. G-Protein Coupled Receptors (GPCRs) are important as they can transmit messages from a cell’s exterior to its interior, changing that cell’s behaviour. For this reason,

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