OAR@UM (University of Malta) · 1998 · 18 citations · 0 references
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Social SciencesBusiness EconomicsEconomicsLabor EconomicsLabor Market AnalysisEmploymentProduction TheoryProductivity AnalysisFirm-level ProductivityLabor Demand EstimationLabor Demand ModelingManufacturing Productivity
The aerobic glycolysis rate and mitochondria-bound hexokinase activity of ascitic liver cancer cells are 8 and 50 times as high as those of the normal liver cells, and they can be inhibited by Na2SeO3 in concentration below 10 micrograms/ml. The inhibitory effect increases with selenium concentration. In contrast, Na2SeO3 at the same concentration does not significantly affect the glycolysis rate and mitochondria-bound hexokinase activity of the normal liver cells. The selective action of selenium on energy metabolism of the liver cancer cells may account for its inhibitory effect on cancer cells.