Micro-determination of copper in biological material

Abstract

involving unusually large numbers of determinations on blood, tissues, urine, faeces and animal foods, the Tompsett modification [1934, 1] of the method of Apart from the somewhat laborious ashing or tissue extraction procedures, the technique for subsequent deionization of iron was not found universally satisfactory. Although results of the correct order of magnitude were generally obtained, and might therefore not be suspected at sight, the general drift was definitely high and the slightest imperfection in removal of iron from the sphere of reaction seriously affected percentage accuracy as real magnitudes of Cu diminished, so rendering the process uncertain for metabolism work in which an accurate balance sheet was required.