Promoter hypermethylation and homozygous deletion of the p14 ARF and p16 INK4a genes in oligodendrogliomas

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Specific Genetic Predictors of Chemotherapeutic Response and Survival in Patients With Anaplastic Oligodendrogliomas

J. Gregory Cairncross, Keisuke Ueki, Magdelena C. Zlatescu et al. · JNCI Journal of the National Cancer Institute · 1998 · 1.6K citations · Full text

Medicine, Molecular Genetics, Oncology +13

ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways

Yanping Zhang, Yue Xiong, Wendell G. Yarbrough · Cell · 1998 · 1.6K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

Takehiko Kamijo, Jason D. Weber, Gerard P. Zambetti et al. · Proceedings of the National Academy of Sciences · 1998 · 899 citations

Life Sciences, Cell Biology, Molecular Biology +15

Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p.

J. Reifenberger, Guido Reifenberger, L Liu et al. · PubMed · 1994 · 606 citations · Full text

Medicine, Genetics, Molecular Genetics +13