HIV‐1 reverse transcriptase‐associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA.

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

Lori A. Kohlstaedt, J Wang, Jonathan M. Friedman et al. · Science · 1992 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +17

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.

Alfredo Jacobo‐Molina, Jianping Ding, Raymond G. Nanni et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +17

Mechanism and fidelity of HIV reverse transcriptase.

Warren M. Kati, Kenneth A. Johnson, L. Fred Jerva et al. · Journal of Biological Chemistry · 1992 · 491 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Rapid purification of homodimer and heterodimer HIV‐1 reverse transcriptase by metal chelate affinity chromatography

Stuart F. J. Le GRICE, Fiona Grüninger-Leitch · European Journal of Biochemistry · 1990 · 332 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Mechanism of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase

James A. Peliska, Stephen J. Benkovic · Science · 1992 · 330 citations

Life Sciences, Biochemistry, Molecular Biology +10