Haemolytic disease in mice induced by transplantation of hybridoma cells secreting monoclonal anti-erythrocyte autoantibodies.

Abstract

compared with the normalized activityagainst mouseRBC(Table 1).Mice implanted with these hybridomas developedhaemolytic disease, the severity ofwhichvaried withthe particular hybridoma transplanted and with thehistocompatibility relationship between the hybri-doma and the recipient. The results in Table 2