Asparagine endopeptidase deletion ameliorates cognitive impairments by inhibiting proinflammatory microglial activation in MPTP mouse model of Parkinson disease

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

Timothy R. Sampson, Justine W. Debelius, Taren Thron et al. · Cell · 2016 · 3.6K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.

Jonathan A. Javitch, Robert J. D’Amato, Stephen M. Strittmatter et al. · Proceedings of the National Academy of Sciences · 1985 · 1.3K citations · Full text

Medicine, Neuroscience, Pharmacology +17

COGNITIVE DEFICITS IN THE EARLY STAGES OF PARKINSON'S DISEASE

Andrew J. Lees, Eileen Smith · Brain · 1983 · 798 citations

Medicine, Neurology, Neuroscience +17

Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson’s disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling pathway

Mengfei Sun, Yingli Zhu, Zhi-Lan Zhou et al. · Brain Behavior and Immunity · 2018 · 744 citations

Life Sciences, Neurobiology, Neuroscience +17

Caspase signalling controls microglia activation and neurotoxicity

Miguel Ángel Burguillos, Tomas Deierborg, Edel Kavanagh et al. · Nature · 2011 · 590 citations · Full text

Life Sciences, Neurobiology, Neuroscience +12