Edel Kavanagh

Caspase signalling controls microglia activation and neurotoxicity

Miguel Ángel Burguillos, Tomas Deierborg, Edel Kavanagh et al. · Nature · 2011 · 590 citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation

Miguel Ángel Burguillos, Martina Svensson, Tim Schulte et al. · Cell Reports · 2015 · 357 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype

Xianli Shen, Miguel Ángel Burguillos, Ahmed M. Osman et al. · Nature Immunology · 2016 · 104 citations · Full text

Life Sciences, Neuroscience, Oncology +14

Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia

Edel Kavanagh, Johanna Rodhe, Miguel Ángel Burguillos et al. · Cell Death and Disease · 2014 · 81 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner

Katarzyna Mnich, Laura A. Carleton, Edel Kavanagh et al. · Cell Death and Disease · 2014 · 50 citations · Full text

Life Sciences, Cell Biology, Neurobiology +17