Concepedia

Novel histone deacetylase inhibitor CT-101 induces γ-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects

Louis H. Junker, Xingguo Zhu, Ryan E. Cerbone, Clifford L. Hendrick, José Sangerman, Susan P. Perrine, Betty S. Pace

Blood Cells Molecules and Diseases · 2021 · 10 citations · 44 references

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Concepts

References

44

Capturing Chromosome Conformation

Job Dekker, Karsten Rippe, Martijn Dekker et al. · Science · 2002 · 3.8K citations

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Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death

Orah S. Platt, Donald Brambilla, Wendell F. Rosse et al. · New England Journal of Medicine · 1994 · 3.3K citations · Full text

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Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia

Samuel Charache, Michael L. Terrin, Richard D. Moore et al. · New England Journal of Medicine · 1995 · 2.3K citations · Full text

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Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus

Bas Tolhuis, Robert‐Jan Palstra, Erik Splinter et al. · Molecular Cell · 2002 · 1.4K citations · Full text

, , +3

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Matthew C. Canver, Elenoe C. Smith, Falak Sher et al. · Nature · 2015 · 910 citations

, , +11