Physical Chemistry Chemical Physics · 2021 · 27 citations · 79 references
Natural SciencesBiochemistryBiophysicsBiophysical ChemistryStructural BiologySurface ScienceAdsorption At InterfacesBiomolecular InterfacesCoarse-grained ModelingIntermolecular ForcesProtein AdsorptionProtein StructureAdsorption PropertiesCharge DistributionDebye-huckel TheoryDebye-hückel TheoryElectrostatic InteractionsIsoelectric PointLysozyme AdsorptionProtein-surface Interactions
The hen egg-white lysozyme adsorbs into a charged confining pore in two orientations depending on the pH. The p K a of the residues closer to the pore surface is significantly affected by the protein–pore electrostatic interactions.
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