A novel peroxisome proliferator-activated receptor gamma ligand improves insulin sensitivity and promotes browning of white adipose tissue in obese mice

Nonalcoholic Fatty Liver Disease

Giulio Marchesini, Mara Brizi, Giampaolo Bianchi et al. · Diabetes · 2001 · 2.6K citations · Full text

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

Saverio Cinti, Grant A. Mitchell, Giorgio Barbatelli et al. · Journal of Lipid Research · 2005 · 2.4K citations · Full text

Metabolic Disorder, Immunology, Cell Death +23

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

Nataša Petrovič, Tomas B. Waldén, Irina G. Shabalina et al. · Journal of Biological Chemistry · 2009 · 1.2K citations · Full text

Metabolic Remodeling, Cellular Physiology, Thermogenically Competent +17

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

Jang Hyun Choi, Alexander S. Banks, Jennifer L. Estall et al. · Nature · 2010 · 877 citations

Obesity, Metabolic Syndrome, Molecular Pharmacology +8

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

Haruya Ohno, Kosaku Shinoda, Bruce M. Spiegelman et al. · Cell Metabolism · 2012 · 726 citations · Full text

Metabolic Syndrome, Signal Transduction, Lipid Synthesis +7