Activation of AMPKα1 is essential for regulatory T cell function and autoimmune liver disease prevention

Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

Ryan D. Michalek, Valerie A. Gerriets, Sarah R. Jacobs et al. · The Journal of Immunology · 2011 · 2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Reuben J. Shaw, Monica Kosmatka, Nabeel Bardeesy et al. · Proceedings of the National Academy of Sciences · 2004 · 1.8K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Regulatory T cells and Foxp3

Immunological Reviews · 2011 · 754 citations

Life Sciences, Cell Biology, Immunology +17

The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo

Julianna Blagih, François Coulombe, Emma E. Vincent et al. · Immunity · 2015 · 659 citations · Full text

Life Sciences, Cell Biology, Immunology +12

Knockout of the α2 but Not α1 5′-AMP-activated Protein Kinase Isoform Abolishes 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranosidebut Not Contraction-induced Glucose Uptake in Skeletal Muscle

Sebastian B. Jørgensen, Benoı̂t Viollet, Fabrizio Andréelli et al. · Journal of Biological Chemistry · 2004 · 549 citations · Full text

Life Sciences, Biochemistry, Physiology +14