Growing the molecular architecture of imidazole-like ligands in HO-1 complexes

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

Antoine Daina, Olivier Michielin, Vincent Zoete · Scientific Reports · 2017 · 17.1K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacokinetics +16

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

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pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

Douglas E. V. Pires, Tom L. Blundell, David B. Ascher · Journal of Medicinal Chemistry · 2015 · 5.4K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Prediction of Drug Absorption Using Multivariate Statistics

William J. Egan, Kenneth M. Merz, John J. Baldwin · Journal of Medicinal Chemistry · 2000 · 1.9K citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

R Tenhunen, Harvey S. Marver, R. Schmid · Proceedings of the National Academy of Sciences · 1968 · 1.8K citations

Life Sciences, Biochemistry, Physiology +17