Mechanism of total glucosides of paeony in hypoxia/reoxygenation-induced cardiomyocyte pyroptosis

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury

Øystein Sandanger, Trine Ranheim, Leif Erik Vinge et al. · Cardiovascular Research · 2013 · 512 citations

Life Sciences, Cardiology, Immunology +17

NLRP3 Inflammasome Activation‐Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats

Zhen Qiu, Shaoqing Lei, Bo Zhao et al. · Oxidative Medicine and Cellular Longevity · 2017 · 358 citations · Full text

Veterinary Medicine, Cardiology, Pathobiology +16

Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes

Zhen Qiu, Yuhong He, Hao Ming et al. · Journal of Diabetes Research · 2019 · 343 citations · Full text

Life Sciences, Cardiology, Cell Biology +17

Uric acid aggravates myocardial ischemia–reperfusion injury via ROS/NLRP3 pyroptosis pathway

Shichun Shen, Fei He, Cheng Cheng et al. · Biomedicine & Pharmacotherapy · 2020 · 205 citations · Full text

Veterinary Medicine, Cardiology, Pathobiology +16

<p>Emodin alleviates myocardial ischemia/reperfusion injury by inhibiting gasdermin D-mediated pyroptosis in cardiomyocytes</p>

Bozhi Ye, Xudong Chen, Shanshan Dai et al. · Drug Design Development and Therapy · 2019 · 188 citations · Full text

Medicine, Cardiology, Pharmacology +13