Concepedia
The International Journal of Biochemistry & Cell Biology · 2021 · 22 citations · 36 references
Open access
CytokineSignaling PathwayCell RegulationJak-stat Signaling PathwayMedicineImmunologyImmunologic MechanismIncreased MigrationCancer BiologyCell BiologyCell SignalingTumor BiologyOvarian CancerOvarian Cancer Cells
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PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
Michael A. Curran, Welby Montalvo, Hideo Yagita∥ et al. · Proceedings of the National Academy of Sciences · 2010 · 1.8K citations · Full text
Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade
Joseph L. Benci, Bihui Xu, Yu Qiu et al. · Cell · 2016 · 1.1K citations · Full text
Tumor Immunology, Multigenic Resistance Program, Cancer Immunosurveillance +11
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB
Lin Feng Chen · The EMBO Journal · 2002 · 803 citations · Full text
Chromatin, Transcriptional Regulation, Signal Transduction +10
IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer
Kaoru Abiko, Noriomi Matsumura, Junzo Hamanishi et al. · British Journal of Cancer · 2015 · 689 citations · Full text
CTLA-4 blockade increases IFNγ-producing CD4 <sup>+</sup> ICOS <sup>hi</sup> cells to shift the ratio of effector to regulatory T cells in cancer patients
Chrysoula I. Liakou, Ashish M. Kamat, Derek Ng Tang et al. · Proceedings of the National Academy of Sciences · 2008 · 535 citations · Full text