Publication | Open Access

Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O6-methylguanine DNA methyltransferase (MGMT) expression and reactive oxygen species (ROS)-mediated DNA damage in glioblastoma

O6-methylguanine Dna MethyltransferaseTumor BiologyNeuro-oncologyReactive Oxygen SpeciesGliomaOncogenic AgentSerine Synthesis EnhancesMedicinePharmacologyCancer BiologyAnti-cancer AgentHigh-grade GliomasCancer TreatmentOncologyCell BiologyCancer Research