Concepedia

Tox2 is required for the maintenance of GC T <sub>FH</sub> cells and the generation of memory T <sub>FH</sub> cells

Shu Horiuchi, Hanchih Wu, Wen‐Chun Liu, Nathalie Schmitt, Jonathan Provot, Yang Liu, Salah-Eddine Bentebibel, Randy A. Albrecht, Michael Schotsaert, Christian V. Forst,

Science Advances · 2021 · 39 citations · 32 references

DOIFull text

Open access

Concepts

Abstract

Transcription factor Tox2 plays a key role to maintain T FH phenotype and generate memory T FH cells in both mice and humans.

References

32

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

Rimpei Morita, Nathalie Schmitt, Salah-Eddine Bentebibel et al. · Immunity · 2011 · 1.6K citations · Full text

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Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

Michela Locci, Colin Havenar‐Daughton, Elise Landais et al. · Immunity · 2013 · 894 citations · Full text

, , +12

Imaging of Germinal Center Selection Events During Affinity Maturation

Christopher D.C. Allen, Takaharu Okada, Hao Tang et al. · Science · 2006 · 770 citations

, , +17

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8 <sup>+</sup> T cell exhaustion

Hyungseok Seo, Joyce Chen, Edahí González‐Avalos et al. · Proceedings of the National Academy of Sciences · 2019 · 769 citations · Full text

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Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure

Jing He, Louis M. Tsai, Yew Ann Leong et al. · Immunity · 2013 · 654 citations · Full text

, , +14