Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus

Huai‐Chia Chuang, Wei‐Ting Hung, Yi‐Ming Chen, Pu‐Ming Hsu, Jeng‐Hsien Yen, Joung‐Liang Lan, Tse‐Hua Tan

Annals of the Rheumatic Diseases · 2021 · 12 citations · 17 references

DOIFull text

Open access

Abstract

Multiple GLK germline and somatic variants cause GLK induction by increasing mRNA or protein stability in patients with SLE.

References

17