Concepedia

Publication | Open Access

Aristolactam BIII, a naturally derived DYRK1A inhibitor, rescues Down syndrome-related phenotypes

DOIFull Paper Access

22

Citations

57

References

2021

Year

Miri Choi, Ae‐Kyeong Kim, Youngwook Ham, Joo‐Youn Lee, Dae-Yong Kim, Ansook Yang, Min Ju Jo, Eunyoung Yoon, Jung‐Nyoung Heo, Sang‐Bae Han,
Phytomedicine

Abstract

Our work revealed that aristolactam BIII as a novel DYRK1A inhibitor rescues DS phenotypes in cells and in vivo and suggested its therapeutic potential for the treatment of DYRK1A-related diseases.

References

YearCitations

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