Tryptophan potentiates CD8<sup>+</sup> T cells against cancer cells by TRIP12 tryptophanylation and surface PD-1 downregulation - Concepedia

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Tryptophan potentiates CD8<sup>+</sup> T cells against cancer cells by TRIP12 tryptophanylation and surface PD-1 downregulation

DOI Full Paper Access

90

Citations

40

References

2021

Year

Rui Qin, Chen Zhao, Chenji Wang, Wei Xu, Jian‐Yuan Zhao, Yan Lin, Yiyuan Yuan, Pengcheng Lin, Yao Li, Shimin Zhao,

Journal for ImmunoTherapy of Cancer

Abstract

Our results revealed the immune-activating efficacy of tryptophan, and suggested tryptophan supplemental may benefit IDO inhibitors and PD-1 blockade during anticancer treatments.

References

	Year	Citations

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