Journal of Biomedical Research · 2021 · 118 citations · 33 references
Life SciencesBioengineeringBiotechnologyBiomaterialsNanobiotechnologyTissue EngineeringGlycan BiosynthesisGlycan StructureMicrobial BiopolymersNanobiomaterialsPolysaccharide PropertiesPolysaccharide StructureBacterial Cellulose ProductionBacterial PolysaccharidesBiomedical ApplicationsMicrobial Polysaccharide ProductionPolysaccharide Materials
using simple culturing methods to allow inexpensive and environmentally friendly small- and large-scale production. Depending on the growth media and types of fermentation methods, ultra-pure cellulose can be obtained with different physio-chemical characteristics. Upon biosynthesis, bacterial cellulose is assembled in the medium into a nanostructured network of glucan polymers that are semitransparent, mechanically highly resistant, but soft and elastic, and with a high capacity to store water and exchange gasses. BNC, generally recognized as safe as well as one of the most biocompatible materials, has been found numerous medical applications in wound dressing, drug delivery systems, and implants of heart valves, blood vessels, tympanic membranes, bones, teeth, cartilages, cornea, and urinary tracts.
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Bacterial synthesized cellulose — artificial blood vessels for microsurgery
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Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid
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