Durable complete response to pembrolizumab in microsatellite stable colorectal cancer

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Dung T. Le, Jennifer N. Uram, Hao Wang et al. · New England Journal of Medicine · 2015 · 9.4K citations · Full text

Life Sciences, Immunology, Oncology +17

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

Michael J. Overman, Ray McDermott, Joseph L. Leach et al. · The Lancet Oncology · 2017 · 2.8K citations · Full text

Medicine, Genetics, Oncology +14

Safety and antitumor activity of the anti–PD-1 antibody pembrolizumab in patients with advanced colorectal carcinoma

Bert H. O’Neil, John M. Wallmark, David Lorente et al. · PLoS ONE · 2017 · 305 citations · Full text

Medicine, Oncology, Pharmacology +17

Response to PD-1 Blockade in Microsatellite Stable Metastatic Colorectal Cancer Harboring a<i>POLE</i>Mutation

Jun Gong, Chongkai Wang, Peter P. Lee et al. · Journal of the National Comprehensive Cancer Network · 2017 · 208 citations · Full text

Life Sciences, Immunology, Oncology +17

Clinical activity and safety of cobimetinib (cobi) and atezolizumab in colorectal cancer (CRC).

Johanna C. Bendell, Tae Won Kim, Boon Cher Goh et al. · Journal of Clinical Oncology · 2016 · 161 citations

Medicine, Oncology, Pharmacology +17