Nature Communications · 2021 · 67 citations · 23 references
Veterinary MedicineImmunologyInfectious DiseasesEpidemiologyInfectious Disease EpidemiologyPublic Health SurveillanceAfrican Health StudiesSeroprevalence StudiesSusceptibility To InfectionTropical MedicineViral EpidemiologyInfection-related MortalityPandemic Spread PatternsSars-cov-2 InfectionTemporal Trends In Mortality
Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.
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A serological assay to detect SARS-CoV-2 seroconversion in humans
Fatima Amanat, Daniel Stadlbauer, Shirin Strohmeier et al. · Nature Medicine · 2020 · 2K citations · Full text
Seroprevalence of anti–SARS-CoV-2 IgG antibodies in Kenyan blood donors
Sophie Uyoga, Ifedayo Adetifa, Henry Karanja et al. · Science · 2020 · 352 citations · Full text