Decreased number of p16-positive senescent cells in human endometrium as a marker of miscarriage

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Darren J. Baker, Tobias Wijshake, Tamar Tchkonia et al. · Nature · 2011 · 3.5K citations · Full text

Aging, P16ink4a-positive Senescent Cells, Immunology +6

Estimation of the Youden Index and its Associated Cutoff Point

Ronen Fluss, David Faraggi, Benjamin Reiser · Biometrical Journal · 2005 · 2.5K citations

Data Classification, Classification Method, Youden Index +14

The Inconsistency of “Optimal” Cutpoints Obtained using Two Criteria based on the Receiver Operating Characteristic Curve

Neil J. Perkins, Enrique F. Schisterman · American Journal of Epidemiology · 2006 · 1.7K citations · Full text

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

Jiří Lukáš, David Parry, Louise Aagaard et al. · Nature · 1995 · 895 citations

Tumor Biology, Cell Regulation, Retinoblastoma-protein-dependent Cell-cycle Inhibition +6

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

James Koh, Greg H. Enders, Brian David Dynlacht et al. · Nature · 1995 · 515 citations

Tumour-derived P16 Alleles, Cell Cycle, Tumor Suppressor +4