Concepedia

A biologically stable DNAzyme that efficiently silences gene expression in cells

Yajun Wang, Kim Nguyen, Robert C. Spitale, John C. Chaput

Nature Chemistry · 2021 · 228 citations · 36 references

DOI

Concepts

References

36

A general purpose RNA-cleaving DNA enzyme

Stephen W. Santoro, Gerald F. Joyce · Proceedings of the National Academy of Sciences · 1997 · 1.5K citations

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Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease

Jin‐Kuk Kim, Chunguang Hu, Christelle Moufawad El Achkar et al. · New England Journal of Medicine · 2019 · 805 citations · Full text

, , +17

Inhibiting eukaryotic transcription. Which compound to choose? How to evaluate its activity?

Olivier Bensaude · Transcription · 2011 · 604 citations · Full text

, , +8

Chemical Etiology of Nucleic Acid Structure: The α-Threofuranosyl-(3'→2') Oligonucleotide System

Kai‐Uwe Schöning, Peter Scholz, Sreenivasulu Guntha et al. · Science · 2000 · 550 citations

, , +17

Mechanism and Utility of an RNA-Cleaving DNA Enzyme

Stephen W. Santoro, Gerald F. Joyce · Biochemistry · 1998 · 452 citations

, , +17